nucleus is frequently eccentric and may be slightly 

 indented, and does not stain so deeply as the young 

 nucleus. The protoplasm is fairly wide and often 

 shews some reddish granules with Romanowsky. These 

 forms are not always easily distinguished from large 

 mononuclears, the greater size of the latter and the 

 character of the nucleus are the main distinctive 

 features. These old forms constitute one of the cells 

 known as makrophages. They sometimes contain 

 malaria pigment (Fig. 2). 



Many of the lymphocytes in fresh films shew a 

 spot at the edge of the cell (Manson's spot). The spot 

 looks dark in one focus, light in another, and should not 

 be mistaken for a pigment granule. 



Fig. 3. Myelocytes. Left, Eosinopbil ; right, Neutrophii 



Large Mononudear Leucocyte. 10-20/1, the largest 

 leucocyte in the blood. It has a characteristic irregular 

 much-indented nucleus which stains feebly, quite 

 distinct from that of the old lymphocyte. The proto- 

 plasm is broad and may shew a few azure granules with 

 Romanowsky. It also is a makrophage, and is the 

 typical pigmented leucocyte of malarial blood (Fig. 2). 



Transitional. About the same size as large mono- 

 nuclears, and the nucleus is of the same general nature ; 

 but the lobed indented character is much further 

 developed, being trident or S-shaped. They are not 

 uncommon in malarial blood and are counted with the 

 large mononuclears (Fig. 2). 



