219 



\TT/^I 



It is this ratio -^-^ that it is important to 

 KC 



determine, for unless the red cells are counted as well 

 as the white, little value attaches to the leucocytic 

 value. 



In malaria, we find that we get changes of the 

 following kinds : 



(1) ii a.m., rigor. Red cells = 2,900,000. WC I 

 White cells 10,000 - RC "290 



i.e., leucocytosis. 



(2) 11.30 a.m., rigor completed - = ~z~ 



ixV-/ 74 



i.e., leucopenia. 



WC i 



(3) 2 p.m., temperature 38-2 __ = 



i.e., increased leucopenia. 



The leucocytosis was, in this case, quite transient, 

 followed by a marked leucopenia. 



During the course of an attack, we may have 

 changes of this kind : 



1. Some days before the attack and before 

 parasites appear in the blood, instead of 



WC i WC i . 



= -, =-^ = - -i.e., a leucopenia. 



RC 500 RC 1,000 



2. During the shivering attack and height of 

 the pyrexia, the condition changes to one of leucocy- 

 tosis, so that 



WC i i i 



= _ or even 



RC 300 200 90 



3. This leucocytosis may not last long, but is 



