28 7 



Chronic Form. Follows the acute attack, when 

 the dog does not die or quickly recover. It is 

 characterised by (i) Extreme anaemia ; (2) Emaciation ; 

 (3) Weakness and anorexia. Haemoglobinuria and 

 icterus are not seen unless, as sometimes happens, an 

 acute attack supervenes after partial recovery. The 

 temperature is variable. All grades of severity of 

 attack are seen, and the types acute, chronic and 

 latent cannot be very clearly defined. 



Recovered animals remain infective for a long 

 time, and shew scanty parasites. 



Blood Examination. Snip the extreme point of 

 the ear with a sharp scissors, or in large dogs shave 

 the posterior border and prick with a needle. 



Parasites appear first about the fifth or sixth day 

 after subcutaneous inoculation, and earlier in the case 

 of intravenous inoculation. After the bite of infected 

 ticks they may be seen as early as the fourth day or 

 as late as ten, fifteen or twenty days after. They are 

 abundant in the acute disease, except after a crisis, 

 but scanty in the chronic. They may be abundant at 

 the outset though there are few symptoms. 



Intracorpuscular forms are (i) Pyriform or oval ; 

 (2) Round ; (3) Irregular (amoeboid), and many shew 

 pseudopodia which may be short and thick or very 

 fine resembling flagella (Plate III). 



During growth the parasite is amoeboid, and 

 commonly they stretch themselves nearly across the 

 corpuscle. Division occurs either by the parasite, 

 when in an extended position, becoming constricted in 

 the middle ; or by an amoeboid form dividing into 

 two pyriform halves, each half carrying with it a 

 portion of the chromatin. In this way result two, 

 four, eight, sixteen and even thirty-two parasites in 

 a corpuscle. Single and double forms are always the 



