347 



anaemia and weakness ; (3) The most characteristic 

 symptom is paralysis of the hind quarters. This first 

 shews itself in a dragging of the hoof, and 'progresses 

 until the animal can no longer stand ; (4) Haemo- 

 globinuria is not uncommon ; (5) Oedema is rare ; 

 (6) Eye symptoms also occur. 



i- j._jThe disease is nearly always fatal, and lasts a few 

 days, weeks, or months. In donkeys the disease is 

 chronic, lasting six to twelve months. Cattle, goats 

 and pigs are very refractory to inoculation. 



Blood Examination. Trypanosomes are most 

 easily found during the pyretic periods. A sub- 

 inoculation into a dog or rabbit is often necessary 

 for the detection. 



Morphology. 22-24/4 by 1*5^. The main charac- 

 teristic is the extremely small (? existent) blepharo- 

 plast. 



Pathology. The spleen is much enlarged, also 

 the liver and lymphatic glands. The kidneys shew 

 haemorrhagic nephritis. Effusions occur in the 

 various serous cavities. 



Transmission. The mode is unknown. It is 

 possible that ticks are concerned, for the evidence 

 is rather against biting flies. 



Zousfana. Is possibly a variety of T. equinum. 

 It affects horses in Algeria. Oedema is nearly always 

 absent, and attacks of haemoglobinuria lasting 

 one to two days are common. 



5. T. equiperdum. The cause of Dourine, a 

 disease of horses in Europe, N. America, Algeria 

 (especially), India. 



Symptoms. Three periods are described : 



(i) Period of oedema : Eleven to twenty days 

 after coitus, swellings of the genitalia appear. There 

 is also fever. 



