LEUCOCYTIC CHANGES 



Leucopenia is the most marked change. So much 

 is this so, that it is necessary to take several large films 

 in order to make accurate leucocytic counts. Two 

 thousand leucocytes per mm. 8 is a common value and 

 still smaller numbers are not uncommon. The relative 

 leucocytic values, however, do not vary much from the 

 normal, and are quite unlike those of malaria. 



POST-MORTEM CHANGES 



Spleen. The appearance of the spleen and the 

 liver are almost pathognomonic. The spleen retains 

 its shape when removed from the body as if hardened 

 in situ. It is firm but friable, not tough like a fibroid 

 spleen. 



Liver. Firm but friable, retaining its shape like 

 the spleen on removal. On cutting into it an arbores- 

 cent appearance is noticed, due to the deposit of a white 

 tissue (macrophages containing parasites) in the centre 

 of the lobules. 



