358 BACTERIOLOGY. 



lows this decline in temperature from time to time with 

 the thermometer it will be seen to be gradual and con- 

 tinuous from the time of injection to the death of the 

 animal (Pfeiffer 1 ), which occurs in from eighteen to 

 twenty-four hours after the operation. 



In general, this is the procedure employed in the 

 Institute for Infectious Diseases, at Berlin, tinder 

 Koch's direction. 



* Loc. cit. 



