206 BACTERIOLOGY. 



behaved itself in experiments upon animals 

 very like the actinomyces fungus. 



In glanders, LofHer and Schiitz discovered in 

 1882 minute rods which do not form endo- 

 spores and are joined to one another in short 

 threads ; according to Semmer branching is 

 occasionally shown ; the rods do not stain by 

 Gram's method, and in sections can often be 

 perceived only with considerable difficulty. 

 They grow only at a temperature above 22, 

 and form moist, shiny white layers upon agar 

 and blood serum ; upon potato they develop 

 yellow incrustations, later becoming brown ; 

 virulence is very soon lost. The freshly 

 cultivated bacteria are very virulent and the 

 disease is extremely contagious, so much so, 

 that already two bacteriologists', ProtopopofT 

 and Hofmann von Wellenhof, have lost their 

 lives through accidental self-inoculation. 



Men, horses, mules and asses are especially 

 susceptible to this germ, next stand goats and 

 cats, sheep and dogs are more resistant, and 

 swine still more ; neat cattle are immune. 

 Guinea-pigs and field and wood mice succumb 

 readily to experimental inoculation ; house 

 mice and white mice, on the other hand, are 

 immune. According to Leo, however, white 

 mice succumb if they are made artificially 

 diabetic by feeding with phloridzin. Among 



