380 BACTERIOLOGY. 



munity, first, the isopathic, or homeopathic, 

 that is, the prevention of infectious diseases 

 through inoculation, after the manner of vacci- 

 nation against small-pox, and second the an- 

 tagonistic or allopathic, the utilizing of the 

 antagonistic action of different species of bac- 

 teria in their struggle for food. 



The experiments upon antagonism which 

 were made with living bacteria were repeated 

 by the same observers with the metabolic 

 products of the germs. The result was the 

 same, both for protective and curative pur- 

 poses. 



Romer was the first to prove that it is pos- 

 sible in dealing with animal tuberculosis to 

 obtain the same success with the use of the 

 proteids of other bacteria as was gained with 

 tuberculin. Along the same line, C. Frankel 

 attempted to influence favorably the course of 

 typhoid fever by use of the proteids of the 

 typhoid bacteria, and Rumpf achieved the 

 same result with the proteids of the bacteria 

 of green pus, while other proteids did not work 

 so well. Since these experiments were carried 

 out upon man, I will briefly set forth the 

 results so far as the statements permit of 

 comparison. 



Frankel recorded among 60 cases of typhoid 

 fever, 5 deaths or 8.3 per cent., Rumpf among 



