416 PROCESSES INFERRED FROM DIRECT OBSERVATION 



three per cent, hydrogen peroxide, but T ^ or T ^ pyrogallol will 

 give a bright light, while the light from T ^-?W75- pyrogallol is only just 

 visible. On the other hand f potassium ferrocyanide gives no light 

 with a mixture of -nnr pyrogallol and hydrogen peroxide, while f^- 

 potassium ferrocyanide causes bright light-emission. 



The phenomenon of bioluminescence therefore depends upon the 

 simultaneous presence, in solution, of a special type of oxidizable 

 substance, and an oxidizing agent which presents some analogies to 

 an oxidase, but is thermostabile and diffusible, and to some extent used 

 up in the reaction which it accelerates. 



REFERENCES. 



INTERMEDIATE METABOLISM: 



Pfluger: Pfluger's Arch., 1903, 96, p. 1. 



Van Hoogenhuyze and Verploegh: Zeit. f. physiol. Chemie, 1905, 46, p. 415. 



Knoop: Beitr. z. chem. Physiol. u. Pathol., 1905, 6, p. 150. 



Von Noorden: Metabolism and Practical Medicine, English edition, edited by 

 Walker Hall, London, 1907. 



Shaffer: Am. Jour. Physiol., 1908, 22, p. 445. 



Dakin: Oxidations and Reductions in the Animal Body, London, 1912. 



Taylor: Digestion and Metabolism, Philadelphia, 1912. 



Bloor: Jour. Biol. Chem., 1912, 11, pp. 141 and 429; 1913, 15, p. 105; 1913-14, 16, 

 p. 517; 1914, 17, p. 377; 1914, 19, p. 1; 1915, 22, p. 133; 1915, 23, p. 317. 



Sansum and Woodyatt: Ibid., 1915, 21, p. 1. 



Wilder: Ibid,, 1917, 31, p. 59. 



Hoagland and Mansfield: Ibid., 1917, 31, p. 501. (Glucolysis in Tissue, consult 

 foi literature.) 



Lusk: The Science of Nutrition, Philadelphia, 1919. 

 PRODUCTS OF MUSCULAR ACTIVITY IN STARVATION, ETC : 



Cathcart: Jour. Physiol , 1906-7, 35, p. 500. 



Benedict: Carnegie Institution of Washington Bull., 1907, 77. 



Mendel and Rose: Jour. Biol. Chem., 1911-12, 10, p. 213. 



Mellanby: Proc. Roy. Soc. B., 1912-13, 86, p. 88. 



Meyers and Fine: Jour, Biol. Chem., 1913, 15, p. 305. 



Morse: Jour. Am. Med. Assn., 1915, 65, p. 1613. 

 DIABETES: 



Allen: Glycosuria and Diabetes, Boston, 1913. 



Macleod: Diabetes, its Pathological Physiology, 1913. 



Joslin: The Treatment of Diabetes Mellitus, Philadelphia, 1917. 

 OXIDIZING ENZYMES: 



Bach and Chodat: Centr. f. Biochemie, 1903, 1, pp. 417 and 457. 



Batelli and Stern: C. Rend. Acad. d. Sc., 1905, 140, pp. 1197 and 1352; 1905, 141, 

 p. 139. Biochem. Zeit., 1914, 67, p. 443. 



Kastle: The Oxidases, Hygienic Lab., U. S. A. Pub. Health and Marine Hospital 

 Service Bull., No. 59, Washington, 1910. 



Euler: General Chemistry of the Enzymes, trans, by Pope, New York, 1912. 

 CATALASE: 



Burge; Am. Jour, Physiol., 1916, 41, p. 153; 1916-17, 42, p. 600; 1917, 44, p. 290. 



Burnett: Proc. Soc. Exp. Biol. and Med., 1918, 15, p. 80. 

 BIOLUMINESCENCE : 



Dubois: La Vie et la Lumiere, Paris, 1914. 4 



Harvey: Science, N. S., 1916, 44, p. 652; 1917, 46, p. 241. Am. Jour. Physiol., 

 1916, 41, p. 454; 1916-17, 42, p. 318. Jour. Biol. Chem., 1917, 31, p. 311. Jour. 

 Gen. Physiol., 1918, 1, pp. 133 and 269. 



