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Biological Therapy 



Since serum confers only a passive immunity, it is ad- 

 visable that such immunity be fortified when the animals 

 are a few days old, by the administration of calf scour mixed 

 bacterin. This will result in an immunity which will usually 

 carry the animals past the danger point. For this purpose 

 three injections of two mils each at intervals of five to seven 

 days are recommended. 



CALF SCOUR MIXED BACTERIN 



is recommended for the prevention of calf scour and asso- 

 ciated pneumonia. It should be used in herds where the 

 disease ordinarily does not appear until several days after 

 birth. In herds where the disease appears shortly after birth 

 and serum is used as a prophylactic, the immunity conferred 

 by the serum will be lengthened by the subsequent injection 

 of calf scour bacterin. While good results frequently follow 

 one injection of bacterin, best and most lasting immunity 

 follows three subcutaneous injections of two mils each at in- 

 tervals of five to seven days. The first injection should be 

 given as soon as possible after birth. 



If used as a curative, bacterin should be given in two 

 mil doses each day until improvement is marked. 



Pitman-Moore Anti-Calf Scour Serum and Calf Scour 

 Bacterin are truly polyvalent products and fully capable of 

 accomplishing the objects for which they are intended. All 

 organisms used in the bacterins and as antigens for hyper- 

 Immunizing the horses producing this serum have been iso- 

 lated from acute cases of calf scour and have been collected 

 from many parts of the country. The bacterin is produced 

 in accordance with principles which allow the retention of 

 the full antigenic ability of these bacteria. The serum upon 

 potency test shows an exceedingly high titre which is largely 

 responsible for the exceedingly good results which are at- 

 tributed to this product by leading practitioners in large 

 dairy districts. 



Distemper in Horses 



Distemper, or strangles, is an infectious and highly con- 

 tagious disease of young horses and mules. It is character- 

 ized by catarrhal infiammation of the upper respiratory tract 

 and abscess formation, usually occurring in the glands of 



