Biological Therapy 



135 



much higher, and for successful treatment requires specific 

 biologies other than those ordinarily used for influenza. 



ETIOLOGY. An organism of the hemorrhagic septi- 

 cemia group, B. equisepticum. 



SYMPTOMS. These are the symptoms associated with 

 an acute septicemia and consist of high temperature, rapid 

 onset, labored breathing, prostration and restlessness. The 

 appetite is usually retained until prostration is complete. 



LESIONS. The lesions of this disease in horses are 

 practically the same as are observed in other species of 

 animals affected with the same disease. Petechiation and 

 hemorrhages predominate, particularly on the heart, but 

 these may also be observed on any other organs, while 

 congestion of the lymphatic glands is marked. An excessive 

 amount of straw colored fluid is frequently found in the 

 abdominal or thoracic cavities. If the animal lives through 

 the first few days following the appearance of symptoms the 

 lungs become progressively involved and may be found in all 

 pathological stages from congestion to pneumonia. 



TREATMENT. This should consist of intravenous or 

 subcutaneous injections of Anti-Hemorrhagic Septicemia 

 Serum (Equine). Doses should consist of 50 to 200 c.c. and 

 should be repeated each 12 to 24 hours until acute symptoms 

 subside. 



PREVENTION. Exposed animals are satisfactorily 

 protected against infection by the use of Hemorrhagic Sep- 

 ticemia Bacterin (Equine) which contains B. equisepticum. 

 Three subcutaneous injections of 2 c.c. each should be 

 administered at intervals of three to seven days. 



Hemorrhagic Septicemia in Cattle 



This is an acute or subacute infectious disease of cattle 

 characterized by involvement of the respiratory, digestive 

 or nervous systems and less frequently involving the skin. 

 Some investigators believe it to be synonymous with "corn 

 stalk disease." It is found in all parts of the United States 

 but particularly in the West. The mortality may be as high 

 as ninety per cent. 



