142 Biological Therapy 



The nervous type is only occasionally observed. In this 

 case animals show symptoms of cerebral disturbances, such 

 as incoordination, blindness, muscular twitching and con- 

 vulsions, all of which may resemble the symptoms of spinal 

 meningitis. In this type symptoms may be entirely absent 

 until the animals are handled, after which the appearance 

 of nervous symptoms or convulsions quickly become ap- 

 parent. 



POST MORTEM LESIONS. In the septicemic type the 

 lesions may closely resemble those found in cholera since 

 in this as in the uncomplicated form of the latter the lesions 

 are those of an acute septicemia, viz.: hemorrhages and pe- 

 techia. These may be observed in any portion or any organ 

 of the body. They tend to be more extensive than in cholera 

 and lack uniformity in' size and shape, rarely being circum- 

 scribed but developing a tendency to coalesce as the disease 

 progresses. The lymphatic glands are congested or en- 

 gorged with less tendency to be sharply petechiated than in 

 cholera. Subserous hemorrhages of the heart and lungs may 

 be marked, which is true also of the mucosa of the bladder 

 and intestines. The mucosa of the bladder may be so thor- 

 oughly hemorrhagic that it has the appearance of being 

 granular. An excessive amount of straw-colored fluid is 

 frequently found in the abdominal cavity. 



PECTORAL FORM. The character of the lesions found 

 varies with the duration of the attack. These may range 

 from petechiation, congestion, red or gray hepatization, to 

 all stages of pneumonia or caseation. Pleuritic complica- 

 tions are frequently observed. Not infrequently there are 

 observed new areas of infection showing bright scarlet 

 petechiation adjacent to extensive chronic lesions. In the 

 more chronic cases abscess formation with encapsulated 

 caseous lesions are observed. The bronchi are filled with 

 mucus practically from the beginning of the infection. In 

 the less severe cases there are varying sized areas of grey 

 or red hepatization having a glassy serous appearance. This 

 condition, if extensive, is responsible for the marbled ap- 

 pearance of the lungs, which is so frequently present. In 

 addition to these localized lesions, hemorrhages and petechia 

 are commonly observed on the heart, particularly on the 

 auricles, or may be seen in any part of the body. This is the 

 type of the disease most frequently seen in swine which 

 have recently been subjected to the simultaneous treatment 

 and is often erroneously diagnosed as a "cholera break." 



