Biological Therapy hs 



PITMAN-MOORE HEMORRHAGIC SEPTICEMIA 

 BACTERIN 



(Swine) 

 This product is prepared in accordance with the most 

 modern ideas of bacterin production. It is thoroughly poly- 

 valent since numerous strains isolated from cases of porcine 

 hemorrhagic septicemia from various parts of the country 

 are used in its production. These strains are kept at the 

 highest possible degree of virulency by frequent animal pas- 

 sages. Strains which do not maintain their virulency to 

 this high degree are discarded. This product is sterilized by 

 chemicals, thus eliminating the objections to the inferior 

 method of sterilization by heat, which process is known to 

 injure the antigenic properties of bacterins. The product is 

 standardized so that each dose (two mils) contains sixty 

 billion killed B. suisepticum. It will be seen from the above 

 that every effort is made to make certain that this product 

 is highly antigenic when leaving the laboratories. In addi- 

 tion, every lot of Pitman-Moore bacterin is most thoroughly 

 examined for sterility and freedom from injurious toxins 

 or aggressins. 



PITMAN-MOORE 

 ANTI-HEMORRHAGIC SEPTICEMIA SERUM 



(Swine) 



This product is made from the blood of horses which 

 are hyperimmunized against B. suisepticum. The same 

 strains of organisms as described under bacterin production 

 are used in hyperimmunizing the horses which are used in 

 the production of this product. Only healthy young horses 

 are used and their immunity is developed by gradually in- 

 creasing doses of antigen. The first injection which the 

 animal receives consists of killed B. suisepticum in small 

 doses. After the animal's immunity has been established by 

 this method it is given minute doses of the living organisms, 

 which doses are gradually increased until the individual 

 withstands enormous intravenous injections of the living 

 organisms. When the horse has reached this point, a trial 

 bleeding is made and tested for potency. If this test proves 

 the serum produced by the animal to be of sufficient po- 

 tency, it is then bled for serum production. The serum is 

 subjected to rigid tests for sterility and to the most scientific 

 serological tests and animal inoculations to prove its 

 potencv. 



