Biological Therapy 



153 



sonable number should be ascertained, by taking at least 

 one temperature to each ten animals. This precaution fre- 

 quently reveals high temperatures in animals showing no 

 symptoms, thus making it possible to notify the owner that 

 infection already exists in the herd. This averts responsi- 

 bility for sickness which is almost certain to follow in such 

 herds and enables the operator to use the larger doses of 

 serum needed, whereas failure to determine this incipient 

 infection causes blame to attach itself to the operator or to 

 the products which he has used. Undoubtedly failure to take 

 temperatures most frequently accounts for the appearance 

 of so-called breaks, due to latent infection. 



DOSE OF SERUM 



Following are the doses as generally recommended: 



WHOLE BLOOD AND CLEAR SERUM 



Suckling Pigs 20 Cc. 



20 to 40 pounds 30 Cc. 



40 to 90 pounds 35 Cc. 



90 to 120 pounds 45 Cc. 



120 to 150 pounds 55 Cc. 



150 to 180 pounds 65 Cc. 



180 pounds and over 75 Cc. 



CONCENTRATED CLEAR SERUM 



Suckling Pigs 15 Cc. 



20 to 40 pounds 25 Cc. 



40 to 90 pounds 30 Cc. 



90 to 120 pounds 35 Cc. 



120 to 150 pounds 45 Cc. 



150 to 180 pounds 50 Cc. 



180 pounds and over 60 Cc. 



Some practitioners regularly use smaller amounts of 

 serum than is given above and apparently obtain satisfac- 

 tory results. While this is frequently possible it is not a 

 safe precedure to follow and the dosage given should be the 

 minimum in any case. If one is to err on dosage it is much 

 safer that it be on the side of larger doses since this will 

 help materially in protecting against breaks due to animals 

 which may be in the incubative stage of hog cholera. Both 

 tables represent only the doses for healthy animals. When 

 infection is present in the herd the dose administered to 

 each individual should be increased at least fifty per cent. 



