Biological Therapy 



If)!) 



swine corresponds on account of the difference in the dosage 

 (See page 153). Equally satisfactory results may be expected 

 following the use of any of the three kinds of anti-hog-chol- 

 era serum. 



PITMAN-MOOKE CLEAR ANTI-HOG CHOLERA SERUM 



This product may be had in either concentrated or un- 

 concentrated form. By means of a special process these 

 sera are rendered perfectly transparent, thereby eliminating 

 the smoky appearance as well as the precipitate which is 

 observed in the ordinary clear serum. The same scientific 

 precautions used in producing and testing our whole blood 

 serum are maintained throughout the production of our clear 

 anti-hog cholera serums. 



Keratitis of Cattle 



This disease is also spoken of as "pink eye" of cattle 

 and infectious ophthalmia. Ordinarily enzootic in type, the 

 disease has frequently assumed epizootic proportions and 

 affected large numbers of cattle over great territories. Blind- 

 ness is a common sequelae while loss of weight and emacia- 

 tion make the disease of economic significance. 



ETIOLOGY. Various organisms have been considered 

 as significant in this respect but none have been definitely 

 proven as the etiological factor. In outbreaks during the 

 past few years B. bovisepticum has been found to be present 

 in practically all cases. 



SYMPTOMS. The disease develops as an acute con- 

 junctivitis with intense lachrymation which becomes muco- 

 purulent and with primary corneal localization. Keratitis 

 usually develops in twenty-four to forty-eight hours after 

 the symptoms of conjunctivitis. The cornea becomes opaque 

 with intense congestion around the corneal border and event- 

 ually this resolves into ulceration. The entire process is 

 accompanied by considerable pain and generalized thermic 

 reaction. 



TREATMENT. Isolation of affected animals is most 

 desirable. 



During the extensive outbreaks which occurred in Illi- 

 nois during 1919, 1920 and 1921 it was found that afflicted 

 animals responded promptly to a bacterin containing B. 

 bovisepticum. Results were equally satisfactory whether 



