Biological Therapy 



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Metritis and Endometritis 



These and other suppurative conditions of the female 

 genitalia are extremely common in cattle following parturi- 

 tion. The condition is seldom sufficiently acute to cause the 

 death of affected animals, but the chronicity of the disease 

 interferes with the normal functional activity of the uterus 

 thus preventing pregnancy and seriously interfering with 

 the breeding efficiency of the affected animals. These in- 

 fections frequently progress through the fallopian tubes to 

 the ovaries causing chronic infection in these organs which 

 results in sterility. 



These conditions although sporadic in type are ex- 

 tremely troublesome in herds in which infectious abortion is 

 prevalent, since in these cases a majority of all cattle are 

 affected after calving. In such cases these complications 

 are more serious than abortion itself, and result in per- 

 manently disabling many cattle, either from sterility or 

 from acute toxemia or bacteremia. 



ETIOLOGY. A variety of bacteria have been associated 

 with this condition. Those occurring most frequently and 

 apparently of the greatest etiological significance are B. 

 pyogenes, B. coli, streptococcus and staphylococcus. 



TREATMENT. For the treatment of this condition we 

 offer Pitman-Moore Metritis Bacterin, which contains 60 

 billion killed bacteria to the dose, as follows: 



This proportion corresponds with the frequency with 

 which the organisms are found to occur in field cases. 



The treatment should consist of subcutaneous injections 

 of two c.c. of the above bacterin, repeated each twenty-four 

 hours until acute symptoms and the profuse vaginal dis- 

 charge are modified. Since three injections ordinarily pro- 

 duce this result, following the use of Metritis Bacterin the 

 duration of the disease is considerable shortened and the 

 breeding efficiency of the animal greatly enhanced. 



PREVENTION. In herds where these conditions are 

 prevalent as a sequelae of abortion the use of metritis bac- 

 terin as a prophylactic reduces the disease incidence. For 



