Biological Therapy 



16' 



eyes. The infection from the nasal passage spreads to 

 the mouth and may involve the larynx and pharynx with the 

 formation of croupous exudates of a diphtheritic nature. 

 This form of the disease is commonly called avian diph- 

 theria. It is accompanied by sneezing and later by dyspnoea 

 which terminates in death. During the period of dyspnoea, 

 breathing is entirely through the mouth which causes a foul 

 odor and intense dryness of the oral membranes. 



The affected birds become extremely dull, inappetence 

 is complete, emaciation is marked, while many birds are 

 comatose for several hours before death. The temperature 

 is elevated and diarrhoea may be present. Death may result 

 in a few days from toxemia, from dyspnoea or from starva- 

 tion. Less frequently the symptoms are of a subacute nature 

 and the birds recover although such birds constitute a men- 

 ace bv acting as carriers. 



SYMPTOMS OF CHICKEN POX OR CONTAGIOUS 

 EPITHELIOMA. These consist of local skin lesions on the 

 unfeathered portions of the body, particularly on the comb, 

 wattles and eyelids. These lesions are wart-like growths 

 which appear as small white tumors rapidly increasing in 

 size and changing in color. From white they become yel- 

 low, then dark brown or black red, varying from one-eighth 

 to one-fourth inch in diameter and covered with a hard dry 

 scab. The virus is contained in these scabs. 



TREATMENT AND PREVENTION OF ROUP. Since 

 the serious symptoms and lesions of this group of conditions 

 are due to bacteria which act as secondary invaders it is but 

 natural that satisfactory results have been obtained with 

 bacterins which contain such bacteria. Results should not 

 be expected in cases where diphtheritic exudates are exces- 

 sive nor where the cheesy deposits have caused considerable 

 tissue destruction. In birds treated before the disease 

 reaches this stage and in birds coming in contact with such 

 cases, properly prepared bacterins offer much encourage- 

 ment. 



PITMAN-MOORE MIXED BACTERIN (FOR FOWL) 



Contains twenty billion killed bacteria per c.c, as 

 follows: 



B. pseudodiphtheria 30 per cent 



Streptococci 30 per cent 



Staphylococci 20 per cent 



B. avisepticum 10 per cent 



B. pyocyaneus 10 per cent 



