168 



Biological Therapy 



These are the organisms, and the proportions in which 

 they are most frequently found in roup. All strains used 

 have been isolated from acute cases of roup and are han- 

 dled in such a manner that their antigenic activities are 

 fully retained. 



DOSE. One c.c. administered subcutaneously beneath 

 the wing. Best results will be obtained by three injections 

 at intervals of three to seven days. 



TREATMENT AND PREVENTION OF CHICKEN POX. 

 All infected and exposed birds should receive three sub- 

 cutaneous injections of Pitman-Moore chicken pox vaccine. 

 These should consist of one c.c. and be administered at inter- 

 vals of three to seven days. This vaccine is an attenuated 

 virus prepared according to the method of Beach from the 

 scab lesions of affected birds. This product is given an ex- 

 piration dating of only two months and is therefore supplied 

 only on direct order to our home office at Indianapolis. This 

 short dating is in accord with the findings of Beach and 

 others, which indicates that a pox vaccine to be effective 

 should be comparatively fresh. 



Scours in Pigs 



This disease of young swine which in a manner corre- 

 sponds to scour in the young of other species, is both epi- 

 zootic and enzootic in type. It generally affects all of the 

 animals in a litter and is accompanied by a heavy mortality. 



ETIOLOGY. Dietary disturbances are undoubtedly a 

 factor by causing a devitalized condition. Following this 

 the bacteria ordinarily present in the intestinal flora find 

 conditions favorable to their increased activity and patho- 

 genicity and invade the circulatory system. The organisms 

 most frequently associated with this condition are B. para- 

 typhosus and B. suipestifer. 



SYMPTOMS. Animals under three weeks of age are 

 most susceptible and this susceptibility decreases with age. 

 The affected animals cease nursing and are noticeably in- 

 active. The temperature becomes elevated and a profuse 

 yellowish or chocolate colored diarrhoea early is apparent. 

 Prostration is marked and is followed by coma and death. 

 When death does not occur the animals generally remain 

 unthrifty and develop necrotic enteritis. On account of the 

 pathological changes in the intestinal tract the food is not 

 assimilated and emaciation becomes marked. 



