was carried out by Kriinig and Paul . These authors tried Ihe 



5. K.ronig,B., and Paul, Th., Die Chemischen Grundlagen der 

 Lehre von der Giftwirkung and Desinfection. Zeitschift fur 

 Hygiene und Infectious Krankhelten. 25: 1-112, 1897. 



effects of various heavy metals in combination with many 

 salts as well as with certain acids and bases. Working main- 

 ly with Bacillus anthracis, they regard the influence of oth- 

 er halogen compounds upon the toxicity of mercuric chloride 

 as probably due to a depression of the ionization of the lat-- 

 ter salt. In this connection they say: "Die Desinfections - 

 wirkung wasseriger MercurichloridlBsungen werden durch Zu- 

 satz von Halogenverbindungen der Metalle und von SalzSure 

 herabgesetzt. Es ist warhscheinlich, dass diese Verminderung 

 der Desinfectionskraft auf einer Ruckdrangung der elektroly- 

 tischen Dissociation beruht" (page 111). 



Clark^ carefully studied the influence of various 



6. Clark, J. F., On the toxic value of mercuric chloride and 

 its double salts. Joxirn. Phys* Chem. 5:289-316, 1901. 



concentrations of sodium chloride upon the toxicity of mer- 

 curic chlorideas regards the process of germination in var- 

 ious fungus spores and seeds and the growth of yeasts and 

 bacteria. He found that the toxicity of the mercuric chlor- 

 ide solution increased with th§ addition of small quantities 



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