298 DISEASES OF TRUE IXFECTIOX 



forms, for instanco a case which we will cite illustrates this. The affected 

 animal twenty-four hours l^efore his death had a hoarse bark, no appe- 

 tite, and the muscles of the mouth appeared normal, he allowed the 

 mouth to be examined and the tongue pressed down to see the throat, 

 there was not the slightest inclination to bite or show any signs of deli- 

 rium or mental aberration; when the animal died he showed great 

 sexual excitement. On post-mortem the stomach was found to contain 

 hay, straw, as well as hair that did not come from his own coat. 



This disease must always be considered fatal. 



The diagnosis of rabies may be complicated by certain conditions 

 present, due to other diseases. This is especially noticed in the mild 

 form and in well-trained affectionate animals which obey their masters 

 to the last. Two instances in which the English setter was under com- 

 plete control; hunted in the field, obeying the whistle and call instantly, 

 and at the same time had every symptom of dumb rabies. Often we 

 see cases where the history is either insufficient or the owner can give 

 none at all. On the other hand, in the furious form, a history, as a rule, 

 is not required, as the disease can be instantly recognized from the 

 appearance of the animal. Great excitement- and restlessness, a ten- 

 dency to escape, biting and delirious actions, rapid emaciation, and 

 debility are characteristics of the furious form of this disease, while 

 great depression and paralysis of the lower jaw are characteristic of the 

 dumb form. In both forms there is a great inclination to gnaw objects. 

 Sexual desire, in the early stage, is prominent. A depraved appetite and 

 altered l^ark, more or less rapid symptoms of paralysis, and the cases 

 being invariably fatal. The post-mortem confirms the disease when 

 we find acute hypersemia of the throat, pharynx, and hemorrhagic 

 erosions on the mucous membrane, also foreign bodies, etc., in the 

 stomach. 



Regarding the presence of sugar in the urine of rabid dogs, that 

 cannot be said to be of special significance, as it is found to be present 

 in other diseases. The presence of the corpuscles of Negri in a suspected 

 animal, on the other hand, must be regarded as a diagnostic symptom of 

 great importance, particularly as it is a means of making a quick diag- 

 nosis. The horn of Ammon is where these corpuscles are found in the 

 largest quantities, and it requires one to be thoroughly familiar with 

 these bodies to recognize them quickly and easily. They are 

 found in particles of the horn of Ammon fixed in Zenker's fluid, and 

 treated with a 10 per cent, solution of osmic acid, then washed thoroughly 

 and then laid in absolute alcohol; this method has the disadvantage of tak- 

 ing some time to accomplish it . The method of Bohne seems to be the most 

 desirable. Mode of procedure: sections one-half to three-fourths mm. 

 thick are cut from the horn of Ammon and put in 15 c.c. of acetone and 



