CONTENTS. 



P.IRO. 



I. INFERIOR DRUGS AND INSIDIOUS METHODS OF DECEPTION 7 



Introduction 7 



Conventional adulterations 



Bleached ginger 9 



Cochineal 10 



Availability of the pure product 10 



Methods of analysis 10 



Accidental adulterations * 12 



Deteriorated drugs 13 



"C. P." chemicals 14 



Adulterations resulting from arbitrary standards - - 16 



Analyses of certain oils and potassium cyanids 17 



Methods of estimating chlorids in soluble cyanids 18 



Intentional adulterations 19 



Siftings and sweepings 20 



A common method of deception 21 



II. ROSE GERANIUM OIL AND ITS SUBSTITUTES 23 



III. PHENACETIN: METHODS OF ANALYSIS AND COMMERCIAL STATUS 27 



Historical review 27 



Phenacetin patents and trade-marks 33 



Methods of manufacture 37 



Physical and chemical tests 38 



The melting point 38 



Solubility 40 



Chemical tests for acetanilid in phenacetin 40 



Bromin test 40 



Saponification test 41 



Mercurous nitrate test 42 



lodophenol test 42 



Isonitril reaction 42 



Conflicting statements regarding the isonitril reaction . 43 



Commercial samples 44 



Various labels 44 



Analytical results 45 



Commerce in phenacetin 46 



5 



