of the upper part of the thighs, and more scattered over the chest 

 and the abdomen. They are not distributed regularly, but are 

 grouped with intervening areas of comparatively free skin, and vary 

 in size -from 2 to 3 and 6 to 8 millimeters in diameter. The 

 smaller ones appear as shotty papules, while the larger ones are 

 distinctly vesicular. Several of these vesicles show depressed areas, 

 which give them the appearance of being umbilicated, although 

 more commonly their surfaces appear wrinkled. On section they 

 are seen to be situated on a fairly well-defined, yellowish, firm 

 nodular base, which extends into the subcutaneous tissue. The 

 eruption on the face seems to be more advanced. On the forehead 

 and cheeks the lesions appear as irregularly circular, raised, dark- 

 red and purble-colored plaques about 1 to 1.5 centimeters in 

 diameter (see PL III, fig. 2). Some of these are rounded and 

 nodular, others flat with depressed center and raised edges. A 

 few present a reddish-yellow, ulcerated center surrounded by raised 

 edges. Two of these nodular plaques occur beneath the skin of the 

 scalp, just above the upper margin of the forehead. 



The tissues just to the right of the nose are so swollen as to 

 close the right eye, which itself does not seem to be affected. A 

 section through these swollen tissues reveals many discrete and 

 confluent, yellowish and grayish, caseous foci, which are surrounded 

 by congested and necrotic tissue and extend to the depth of about 

 an inch from the skin surface. The alse nasi are thickened by 

 similar nodules, and one can be seen on the mucous membrane of 

 the upper lip, just to the left of the nasal fossa. A dirty, puru- 

 lent discharge escapes from the nostrils. Upon opening the nares, 

 the mucous membrane, especially of the right one, is seen to be 

 ulcerated. The ulcerations cover most of the mucous surface of 

 the floor and walls of this nostril and extend upon the inferior 

 turbinated bone. (See PL III, fig. 1.) Small, grayish or yellowish 

 nodules may be seen projecting from the ulcerated surfaces. The 

 right . nostril is not affected to such a marked degree. The eth- 

 moidal cells are filled with purulent matter. The right clavicle 

 is much thicker than the left, but nothing of note is seen on 

 section. 



The thoracic cavity contains no fluid. Both lungs are bound to 

 the thoracic walls by firm, fibrous strings of adhesions. The lungs 

 are emphysematous anteriorly, and posteriorly show considerable 

 hypostatic congestion. On palpation small nodules can be felt 



