DESCRIPTION OF PLATES. 



PLATE I. (Photograph, natural size, by C. H. Martin, photographer of e 

 Bureau. ) Showing a large, confluent, nodular, and ulcerated area 

 on the nasal septum of a horse which died of glanders at the quar- 

 termaster's corral in December, 1903. The submaxillary glands 

 were involved and a number of subpleural nodules were found 

 in the lungs. These nodules had caseous centers and were 

 surrounded by well-defined gelatinous capsules from which 

 the contents could be enucleated. Deeper within the lungs, 

 large, white connective tissue tumors with central areas of 

 softening were found. A couple of pea-sized nodules were seen 

 in the spleen on section. 



Bacterium mallei was found in stained preparations from the 

 nasal ulcers and lung nodules and isolated culturally and by 

 the Strauss method. Cultures were obtained from some of 

 the lung nodules which appeared sterile upon microscopical 

 examination. 



II. (Photograph, natural size, by C. H. Martin. ) Showing another type 

 of ulceration numerous smaller areas of confluent and ulcerated 

 nodules on the nasal septum of a horse which also died of glan- 

 ders at the quartermaster's corral in December, 1903. Bacterium 

 maffe! found microscopically and by culture. 



III. Fig. 1 (painted by T. Espinosa, artist of the laboratory), illustrating 



the ulceration in the right nostril of Case II, human glanders. 

 Fig. 2 (original) shows the appearance of the ulcerated plaques on 



the forehead of Case II, human glanders. 

 Fig. 3 (original) shows a section through a couple of lung nodules 



occurring in Case II, human glanders. 



IV. Fig. 1 (photograph, natural size, by Roman Mercado, assistant pho- 



tographer of the Bureau, ) shows the character of the cutaneous 

 eruption in Case II, human glanders. The variation in size and 

 general lack of umbilication are noteworthy points in differen- 

 tiating it from that of smallpox. On account of shrinkage the 

 skin and pustules appear more wrinkled than they did before 

 removal from the body. 



Fig. 2 (photomicrograph, about X 880, by C. H. Martin) shows 

 the characteristic morphology of Bacterium mallei, as seen in a 

 coverslip preparation from one of the skin pustules of human 

 glanders (Case II) (Carbol fuchsin 1.10). The shape, size, and 

 the irregular staining of the rods, together with the evident 

 nuclear fragmentation, is quite pathognomonic. 



V. (Photomicrograph) low magnification, by C. H. Martin.) Shows 

 a section through one of the skin pustules of human glanders 

 (Case I); Borrell's stain (kindness of Dr. Brinckerhoff). 

 VI. (For description see PL VI.) 



VII. ( After Kitt. ) Illustrating the characteristic stellate cicatrices some- 

 times seen on the nasal mucous membrane in chronic glanders. 



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