52 GLANDS IN HEALTH AND DISEASE 



on anything other than the possibility of an indirect 

 pituitary participation in the dwarfed stature 

 characterizing the many types of infantilism." 



Different parts of the pituitary have different 

 properties. It has recently been shown that in 

 reality the two parts of the pituitary have two 

 very different functions the anterior part being 

 the one that affects stature, and the posterior por- 

 tion the one that influences fat formation and the 

 development of the sexual organs. That the an- 

 terior fragment of the pituitary is the growth- 

 promoting factor may be inferred from an experi- 

 ment already cited: if the entire pituitary is re- 

 moved, death results ; if part of it is removed, and 

 a portion of the anterior lobe remains behind, death 

 does not result, but we get a dwarfed condition. 

 To prove that this dwarfed condition of the animal 

 is the . result of an insufficient anterior lobe of 

 insufficient hormone produced by that lobe and 

 not due to the removal of the posterior portion, the 

 latter alone may be removed, when it will be seen 

 that there is no alteration in stature. 



The growth-promoting factor in the pitwtary. 

 Professor Kobertson, formerly at the University of 

 California, and now at the University of Adelaide, 

 Australia, has published an extensive series of 

 studies within the past few years on the growth- 

 promoting factor in the anterior lobe of the pitui- 

 tary. He has isolated a substance from it which he 



