THE NERVOUS SYSTEM 179 



to Cannon, the emotions arouse the adrenals to 

 particular activity, an increased quantity of adrena- 

 line then appears in the blood, and this in turn 

 interferes with normal carbohydrate metabolism 

 to such an extent that an abnormal quantity of 

 sugar finds its way into the blood, giving rise to 

 hyperglycemia. 



"We have recently," write Drs. Stewart and 

 Kogoff, "studied the question whether adrenaline 

 secretion of the adrenals is indispensable for the 

 production of certain experimental hyperglycemias. 

 The majority of previous investigations have suf- 

 fered from the defect that they were carried out, 

 if not on practically moribund animals, at least on 

 animals still under the effects of a serious opera- 

 tion. This undoubtedly is the chief reason for the 

 astonishing lack of uniformity in the results. 

 Working with animals (cats) in which the adrena- 

 line secretion was abolished or reduced to an in- 

 significant fraction of the normal by removal of 

 one adrenal and section of the nerves of the other 

 (an operation which does not preclude the contin- 

 ued life of the animal in good health), we were 

 able to show that two forms of experimental hyper- 

 glycemia that produced by ether and that pro- 

 duced by asphyxia are as readily obtained in the 

 absence of adrenaline secretion as when the adre- 

 nals have not been interfered with." What, then, 

 have the adrenals got to do with hyperglycemia? 



