REFERENCES 209 



the interior or upon the exterior of the body. The first 

 phase he called 'secretion/ the second, 'excretion.' ): 



A. A. Berthold: "Transplantation der Hoden" (Archiv 

 fur Anatomie und Physiologic, page 42, 1849). 

 Berthold removed the testicles from cocks and grafted 

 them to other parts of the body. He observed that "the 

 animals retained their male characteristics in regard to 

 voice, reproductive instinct, fighting spirit, and growth 

 of comb and wattles." 



Thomas Addison : On, the Constitutional and Local Effects 

 of the Disease of the Suprarenal Bodies (London, 1855). 

 An account of the now well-known "Addison's Disease." 



Claude Bernard: Legons sur les proprietes physiologiques 

 et les alterations pathologiques des liquides de I'organ- 

 isme (Bailliere et Fils, Paris, 1859). 

 Here we find the first clear accounts of glandular or- 

 gans that distribute their products by means of the blood 

 stream. The very name "internal secretion" is due to 

 this illustrious Frenchman. 



Theodore Kocher: "Ueber Kropfexstirpation und ihre 

 Folgen" (Archiv fur Iclinische Chirurgie, volume 29, 

 1883). 

 Myxedema is due to the loss of the functional activities 



of the thyroid gland. 



M. Schiff: "Bericht iiber eine Versuchsreihe betr. die 

 Wirkungen d. Exstirpation der Schildriise" (Archiv 

 fur experiment elle Pathologic und Pharmakologie, 

 volume 18, 1884). 



