56 CO/Lr-TAR COLORS USED IN F001> PRODUCTS. 



hours. A much stronger solution, 1:150, is required to kill the typhoid bacillus ii 

 the same time. Malachite Green is said to possess even greater germicidal power thai 

 pyoktanin. Methylene Blue also possesses considerable germicidal power. 



IX, COMPILATION UNDER THE GREEN TABLE NUMBERS OF AL] 

 INFORMATION AVAILABLE AS TO THE SUITABILITY OF COAL- 

 TAR COLORS FOR FOOD. 



GENERAL STATEMENTS. 



Before entering upon a detailed study of what has been publishec 

 for and against specific coal-tar colors, it is probably well to consider 

 for whatever they may be worth, some of the general statements thai 

 have been made, from time to time, hi the literature relative to coal- 

 tar colors, considered either as a whole or as subdivisions or classes 

 thereof, and their physiological action or their suitability for use in 

 foods. 



1. Schultz (Die Ohemie des Steinkohleniheers, Brunswick, 1887-1890 

 Vol. II, p. 35), after discussing the regulations of the German Empin 

 in respect to food coloring, says: 



With respect to these regulations the artificial organic coloring matters can be 

 regarded, in general, as harmless. For the purposes of dyeing magenta made by 

 means of arsenic acid, further picric acid, and those coloring matters which occur as 

 oxalates or zinc chlorid double salts, such as Methylene Blue and Bitter Almond Oi 

 Green, can be used. The use of the substances named for the coloring of food products 

 is, however, suspicious and should not be permitted. 



2. Stilling (Anilinfarbstofe als Antiseptica, Strassburg, 1890, Vol 

 II, pp. 55-56) says: 



In view of the fact that the most innocent substance, such as distilled water or com 

 mon salt, when introduced in large quantities into the organism can act fatally, the 

 anilin coloring matters therefore, particularly if they be free from all admixtures, such 

 as arsenic, copper, and chlorid of zinc, are to be regarded as wholly nonpoisonous. 



All experience gathered since my first publication has likewise fully confirmed this 

 nonpoisonous nature. 



3. Stilling (Ber. Klin. Wochensch. 1890, p. 531) also says: 



Proceeding from purely theoretical views, and based upon these botanical anc 

 physiological experiments, I have recommended anilin colors as antiseptics for th( 

 following reasons: 



1. They are to be designated as absolutely nonpoisonous. This will be confirmee 

 by every chemist acquainted with the relevant details, and also from the medical sid< 

 this has long ago been determined by Grandhomme. The publications of this author 

 who made extensive observations and experiments in the anilin factory of Meister 

 Lucius & Bruening, appeared in the beginning of the eighties, and has hardly becom< 

 known in medical circles. However, I was first made acquainted with this by my 

 colleague, Prof. Rose, in Strasburg. 



2. That it is possible to bring about death in experimental animals by introducing 

 large amounts of the coloring matter into the peritoneal cavity proves nothing against 



