70 



COAL-TAR COLORS USED IN FOOD PRODUCTS. 



effects as above set forth; but this tabulation must not be taken to 

 mean that these dyes can not, under any conditions whatever, produce 

 untoward results ; the reverse is true in most cases. 



EXPERIMENTS ON HUMAN BEINGS. 



The Green Table numbers of those colors concerning which experi- 

 mental data are available on humans are as follows : 1 ; 2 ; 3 ; 4/ 6 ; 

 9; (17,18,41); 55; 65; 85; 86; 95; 102; 103; 105; 106; 107; 197; 

 427; 428; 448; 462; 532; 602; 650. 



The symptoms produced are classified in the following list: 



Internally administered. 



Not poisonous 



4; 



9; 55; 65; 85; 95; 102; 



103 ; 105 ; 106 ; 107; 448 ; 462 

 Poor general condition ---- . ---- 86; 650 



Fever ........................... 2 



Loss of appetite .................. 2 



Vomiting .................. 3; 532; 650 



Intestinal irritant ................ 650 



Diarrhea ...................... 532; 650 



Bladder irritant ................. 650 



Colored urine ............... 86; 95; 650 



Albuminuria 



Increased micturition 



Irritant 



Inflammation 



Dryness of throat. . . . 



650 

 650 

 532 

 532 

 86 



Bad taste in mouth 86 



Restlessness 86 



Rush of blood to head 86 



Vertigo 86; 650 



Headache 650 



Delirium 650 



Twitching of muscles 650 



Yellow coloration of skin 3 



Yellow-colored mucous membrane. 3 

 Food colored with it made a family 



sick 3 



Adults withstand 1 



Children and weak adults do not 



withstand . . 1 



Deaths 2; 3 



Autopsy l 3 



It should be noted that of the 13 dyes here classed as not poisonous 

 to humans all but No. 102 were on the United States market in the 

 summer of 1907, as is shown in the following table: 



Number of dealers offering these nonpoisonous colors in 1907. 



i On permitted list, Food Inspection Decision 76. 

 Symptoms produced by external application of certain colors (Green Table numbers}. 



Burning 2; 427; 428 Dermatitis 4 



Itching 2; 6; 427; 428 Eczema (17, 18, or 41); 197; 602 



Blisters 2; 6 Inflammation 427; 428 



Swelling 427; 428 



It should be noted that No. 86 has been tried on humans and has 

 been found not to produce diarrhea or vomiting. 



Hemorrhagic gastritis. 



