COMPILED DATA UNDER GREEN TABLE NUMBERS. 



71 



G. T. 3 has apparently killed a human at 60 mg per kilo and the 

 autopsy disclosed hemorrhagic gastritis. G. T. 448 has been sug- 

 gested as a possible remedy for Bright's disease. It should also be 

 borne in mind that adults can stand G. T. 1 in doses of 540 to 900 mg 

 daily for a long time, whereas children and weak adults stand that 

 substance only poorly. 



EXPERIMENTS ON SMALL ANIMALS. 



Results of experimenting on rabbits with 10 coal-tar dyes whose 

 Green Table numbers are 1, 2, 86, 89, 107, 427, 448, 504, 517, and 

 563 have been tabulated as follows: 



Paralysis 427* 



Cramps 427* 



No harm produced. 89; 107; 448; 504; 517 



Death 1; 2; 427*; 563* 



Diarrhea 1 



Colored urine 86 



Softened feces 86 



In the case of the numbers marked with an asterisk the color was 

 administered hypodermically. In this connection reference should 

 also be had to the paper of Penzoldt abstracted in Section VIII, 

 page 55. 



The four coal-tar dyes 55, 103, 425, and 480 have been tested on 

 guinea pigs and no disturbance was noticed in all, but in the case of 

 103 occasional thirstiness was observed. No. 448 has been fed to 

 hens without damage, and No. 2 has been recommended as an insect- 

 icide, a fungicide, and a mouse poison. 



GENERAL STATEMENTS. 



The following statements may be of interest before the detailed 

 compilation is read: 



1. O. Buss (Forschungsber. uber Lebensmittel, 1896, vol. 2, pp. 

 163-197, 237}, in a paper entitled "Contributions to the Spectrum 

 Analysis of some Toxic and Pharmacognostically Important Coloring 

 Matters, with Special Consideration to the Ultra- Violet," cites as 

 poisonous the following (Green Table numbers follow in parentheses 

 wherever connection could be satisfactorily established) : 



Picric Acid (1) 



Dinitro o- and p-Cresol (2) 



Martius Yellow (3) 



Aurantia (6) 



Fast Yellow (8) 



Orange II (86) 



As nonpoisonous: 



Naphthol Yellow (4) 



Eosin ." (512) 



Erythrosin (517) 



Anilin Blue (457) 



As doubtful: 

 Methyl Violet (451,454) | Vesuvin. 



Metanil Yellow (95) 



Corallin (483) 



Safranin (584) 



Methylene Blue (650) 



lodin Green (459) 



Alizarin Blue S (563) 



Naphthol Green (398) 



Malachite Green (427, 428) 



Dahlia (450,451) 



(197,201) 



