COMPILED DATA UNDER GREEN TABLE NUMBERS. 93 



FAVORABLE. 



1. Permitted by Confectioners' List. 



2. WEYL (p. SI}: "According to Cazeneuve and Lupine's experiments, the following 



are not poisonous to human beings and dogs: * * * Orange * * *." 



3. " Orange I (Alpha-naphthol Orange, Tropaeolin 000) not poisonous to dogs neither 



by administration by stomach, nor by injection into blood." (On authority of 

 Cazeneuve and Lupine.) (p. 115.) 



4. WEYL (pp. 123, 148) refers to this as not poisonous. 



5. Permitted by the law of Italy. 



6. Permitted by the law of Austria. 



7. CAZENEUVE (Arch. gen. de med., 1886, Vol. I, p. 753) says it may be taken without 



effect by man or animals, sick or well, in large doses. 



8. CAZENEUVE AND LEPINE (Bull, de I'acad. de med., 1886, p. 643): Tolerated by man, 



well or sick. 



G. T. 86. 



Trade names. Orange II; Betanaphthol Orange; Tropseolin OOO 

 No. 2; Mandarin G extra; Chrysaurein; Gold Orange; Orange extra; 

 Atlas Orange; Orange A. 



Names under which it was offered on the United States marlcet as a 

 food color in 1907. Naphthol Yellow SLOZ; Orange II; Orange; 

 Orange Y; Mandarin G extra; Orange A 1201; Orange A extra. 



Scientific name. Sodium salt of para-sulphobenzene-azo-beta- 

 naphthol. 



Discovered. 1876. 



Shade. Orange. Offered by 8 out of 12 sources. 



FAVORABLE. 



1. Permitted by law in Italy. 



2. FRENTZEL (Zts. Nahr. Genussm.,1901, v. 4, p. 974) says that according to his experi- 



ments this color, in the small amounts in which it is used in food products and 

 which can enter the human system in the course of 24 hours, can hardly, even 

 with frequent administration, cause a harmful effect. 



3. FRENTZEL (Zts. Nahr. Genussm., 1901, v.4,pp. 968-974) : Experimented on rabbits, 



giving dye with food, a total of 21 grams in 19 days, a total of 8,748 milligrams 

 per kilogram body weight, or 6,133 grains per 100 pounds body weight, in doses 

 of 1 gram each, daily for the first 15 days, or about 417 milligrams per kilogram 

 of body weight, or 292 grains per 100 pounds body weight per dose for these 15 

 doses; the color could only be detected in the urine, and the feces became 

 softer. A dog was given 1,020 milligrams per kilogram body weight, or 714 

 grains per 100 pounds body weight, and showed distinct kidney irritation, great 

 thirst, and diarrhea; recovery required about one week; and thereafter the same 

 animal was fed by the mouth one-twentieth of the above dose each day for 9 

 successive days without any untoward effect. A second dog received per kilo- 

 gram of body weight 172 milligrams, or 121 grains per 100 pounds body weight, 

 and it, like the first dog, in the first experiment, showed kidney irritation, 

 diarrhea, and great thirst. On humans 100 milligrams, or 1 grains, colored 

 the urine within 15 minutes, and this color remained for 24 hours; there was no 

 sign of vomiting or diarrhea; the bitter taste of the color was noticeable. 



