108 COAL-TAB COLORS USED IN FOOD PRODUCTS. 



3. A. A dog received 167 milligrams per kilogram body weight, or 117 grains per 

 100 pounds body weight each day for 3 successive days; no color was admin- 

 istered for the next 2 days, and the third day the dose was double the former 

 dose. The urine was colored bluish-black and contained albumen. Two days 

 afterward the same dose was given ; urine of intense dark-blue color, and con- 

 tained unaltered coloring matter, which disappeared in 48 hours. Albuminuria 

 continued for about 15 days. (p. 137.) B. "Wool Black is nonpoisonous both 

 by gastric and by subcutaneous administration." (p. 137.) 



G. T. 169. 



Trade names. Crocein Scarlet 7 B; Ponceau 6 RB; Crocein 

 Scarlet 8 B. 



Names under which it was offered on the United States market as a 

 food-color in 1907. Sodium salt of sulpho toluene- azo-tolu ene-azo- 

 bet a-naphthol-alpha-sulphonic acid . 



Discovered and patented. 1881. 



Shade. Red. Offered by 1 out of 12 sources. 



FAVORABLE. 



1. Permitted by Confectioners' List. 



G. T. 188. 



Trade names. Naphthol Black B; Brilliant Black B. 



Name under which it was offered on the United States market as a food- 

 color in 1907. Naphthol Black BDF. 



Scientific name. Sodium salt of disulpho-beta-naphthalene-azo- 

 alpha-naphthalene-azo-beta-naphthol-disulphonic acid. 



Discovered and patented. 1885. 



Shade. Black. Offered by 1 out of 12 sources. 



FAVORABLE. 



1. Permitted by Confectioners' List. 



2. WEYL (p. 138): A. A dog received 112 milligrams per kilogram body weight, or 



78 grains per 100 pounds body weight, daily for 3 successive days; distinct 

 albuminuria, uncolored urine; blue-colored feces; thereupon the daily dose was 

 increased to 187 milligrams per kilogram body weight, that is, 131 grains per 

 100 pounds. No color was administered for 6 days, and during this time the 

 urine was colored from reddish- violet to a bluish-black red ; thereupon the last 

 dose was doubled and 24 hours afterwards that dose was doubled; rather much 

 albumen in urine which was bluish; albuminuria continued for about a week. 

 B. A dog received 222 milligrams per kilogram body weight, or 155 grains per 

 100 pounds daily throughout a whole month; it remained entirely well with 

 good appetite. 



3. "This color is harmless when administered by the stomach, but poisonous sub- 



cutaneously." (p. 140.) 



4. SCHACHERL: Not harmful under conditions in which it is used. 



UNFAVORABLE. 



1 WEYL (p. 139): Where a dog, receiving subcutaneously 31 milligrams per kilogram 

 body weight, or 22 grains per 100 pounds body weight, subcutaneously, died 

 apparently wholly as a result of the color. 



