156 COAL-TAR COLORS USED IN FOOD PRODUCTS. 



398. Naphthol Green B: 



600 grains produced green urine and conjunctiva. 



292 grains produced no effect. 



128 grains produced green urine and conjunctiva. 



II. Those colors that have not been observed to give negative 

 results, but which have caused certain effects: 



11. Sudan I: 



118 grains produced colored urine, vomiting, and albuminuria. 

 17 and 18. Chrysoidin Y and R: 



79 grains produced albuminuria. 



74 grains for 30 days produced no albuminuria, but a loss of 12 J per cent oi 



body weight. 

 88. Diphenylamin Orange: 



216 grains produced albuminuria. 



128 grains produced phenol in urine and albuminuria. 

 138. Fast Brown G: 



237 grains produced diarrhea and loss of appetite. 



218 grains produced diarrhea. 



III. Rabbits: 



1. Picric Acid: 



24.5 grains for 90 days, no effect. 



45 grains for 19 days kill. 

 86. Orange II: 



292 grains, no effect. 



933 grains kill. 

 95. Metanil Yellow: 



216 grains, no effect. 



IV. Humans: 



1. Picric Acid: 



8.3 grains no effect. 

 13.8 grains no effect. 

 Invalids and children can not stand this color. 



2. Dinitrocresol: 



42 grains kill. 

 86. Orange II: 



1 grains, no effect. 



3 grains, headache, vertigo, dryness of throat, and poor general condition. 

 95. Metanil Yellow: 



1 grains, no effect. 



3 grains, no effect. 



From Classes I and II above, it would seem to appear 



(a) That if a dog is killed the color is harmful, even though it take as much as 603 

 grains, or as little as 20.4 grains per 100 pounds body weight to kill. 



(&) That if albuminuria is produced in dogs by as little as 79 grains, or as much ag 

 128 grains, the color is harmful. 



(c) That if diarrhea is produced in dogs by as much as 218 grains, or as little as 50 

 grains, the color is harmful. 



(d) That even if a dog can take as much as 407 grains, the color may be harmful. 



