(JHAI-. i.] TISSUES AND MECHANISMS OF DK.I.M l<>\. 845 



If a piece of a gland which has been secreting for some time, 

 and is therefore a discharged gland, be examined in the same way 

 (Fig. 80 b) the granules are far less numerous and largely con fined 

 t ( ) the part of the cell nearer the lumen, the outer j>urt of the 

 cell around the nucleus consisting of ordinary ' protoplasmic ' cell- 

 . substance. The distinction however between an inner ' granular 

 zone ' next to the lumen and an outer ' clear zone ' next to the 

 basement membrane is less distinct than in the pancreas, partly 

 because the granules do not disappear in so regular a manner as 

 in the pancreas and partly because the outer zone of the mucous 

 cell, as it forms, is less homogeneous than that of the pancreatic 

 cell. 



The ' granules ' or ' spherules ' of the mucous cell are moreover 

 of a peculiar nature. If the fresh cell, shewing granules, (either 

 many as in the case of a loaded or few as in the case of a dis- 

 charged cell) be irrigated with water or with dilute acids or dilute 

 alkalis the granules swell up (Fig. 80 a' b') into a transparent 

 mass, giving the reactions of mucin, traversed by a network of 

 ' protoplasmic ' cell-substance. In this way is produced an ap- 

 pearance very similar to that shewn in sections of mucous glands 

 hardened and stained in the ordinary way. 



In the loaded mucous cell in such hardened and stained pre- 

 parations (Fig. 81 a) there is seen a small quantity of protoplasmic 



FIG. 81. ALVEOLI OF DOG'S SUBMAXILLARY GLAND HARDENKP i\ M < OHOL 

 AND STAINED WITH CARMINE. (Langley.) (The network is diagrammatic.) 



a, from a loaded gland. 



ft, from a discharged gland ; the chorda tympani having bwn stimulated at short 

 intervals during five hours. 



cell-substance gathered round the nucleus at the outer part of the 

 cell next to the basement membrane; the rest of the coll ro- 

 of a network of cell-substance, the interstices being filled with 



