i 9 4 



children respectively ; nay, more, cases have frequently 

 occurred even among the collateral and more distant relatives 

 of diabetics. I feel assured that time and increased ex- 

 perience are alone wanting to substantiate the views held in 

 the foregoing pages as to the influence of heredity in the 

 production and development of morbid conditions generally, 

 and for the reasons assigned viz., that the inheritance of 

 physiological and psychological peculiarities necessitates the 

 inheritance of those which are pathological. 



Epilepsy, mental affections, and other diseases of the 

 nervous system are often intimately associated with diabetes, 

 and this connection is also, in almost every case, due to 

 hereditary predisposition. Cases showing the co-existence 

 of epilepsy, melancholia, etc., are recorded by Seegen, 

 Zimmer, Schmitz, and other authorities. Among the near 

 blood relations of a diabetic patient Langiewicz found 

 epilepsy in seven. One of Griesinger's patients had had 

 epileptic seizures in childhood, and all the brothers and 

 sisters had suffered, or were suffering in the same way. A 

 case is recorded by Lockhart Clarke, in Beale's Archives of 

 Medicine, in which diabetes occurred in an epileptic who 

 died of cerebral softening. 



As to the heredity of diabetes itself, many cases are 

 recorded by P. Frank, Blumenbach, Brisbane, Prout, Pavy, 

 Dickinson, and Senator, and Marsh records the case of a 

 family in which the disease was transmitted even to the 

 fourth generation. From 1868 to 1874, R. Schmitz was 

 enabled to positively affirm the influence of heredity in 22 

 out of 104 cases. 1 



Diabetes Insipidus is also undoubtedly hereditary, and like 

 the mellitic affection is frequently associated with the neuro- 

 1 Senator, 



