84 ANAPHYLAXIS AND ANTI-ANAPHYLAXIS 



anaphylactic disturbances as the albumen contained 

 in serum, milk, or egg-albumen. They shewed, more- 

 over, that the anaphylactic reaction was strictly 

 specific. Thus, the guinea-pigs injected with extract 

 of rice tolerated the injection of other extracts (wheat, 

 sago, kidney beans) very well. Those that were 

 sensitised with extracts of kidney beans did not 

 react when they were injected with extracts of lentils, 

 walnuts, or peas. 



We may note in passing that, according to Cesa- 

 Bianchi and Vallardi,^ animals which have consumed 

 a large quantity of maize afterwards evince a very 

 great degree of sensitiveness in the presence of maize, 

 when injected even in slight doses intravenously or 

 intraperitoneally. This sensitiveness is manifested 

 by excitation phenomena, followed by paralysis, by 

 respiratory troubles, hypothermia, etc., exactly the 

 same as in classical anaphylaxis. 



A large number of researches have been devoted 

 to the study of bacterial anaphylaxis. In spite of the 

 very animated discussions on the subject, the ques- 

 tion even to-day presents more than one point of 

 obscurity. We submit the stages of the process to 

 the reader, so that he may draw his own conclusions 

 from them. 



The symptoms that have been observed to follow 

 repeated injections of bacteria unquestionably recall 

 those which characterise the shock produced by the 

 albumens of serum, milk, or egg-white, the ana- 

 phylactic nature of which could never have been 

 called in question. But is this resemblance to the 

 classical symptoms sufficient to justify the inclusion 

 of the bacterial proteins within the clinical picture 

 of anaphylaxis ? 



One of the outstanding features of anaphylaxis is 

 its specificity, which is in each case more or less 

 * Zeitschr. f. Immunitdtsf., I. Orig., xv., p. 370, 1912. 



