136 ANAPHYLAXIS AND ANTI-ANAPHYLAXIS 



Guinea-pigs, anaphylaxis experi- 

 ments on, with iodoform, gr, 

 92 



with macerations of 



sausages manufactured from 

 different kinds of meat, 94 



95 



with quinine sul- 

 phate, 93 



■ with sodium bro- 

 mide, 93 



in, viii, 3 



— • death, wrongly attributed to 

 anaphylaxis, ix 



— employed for testing of anti- 

 diphtheritic serum, sensitive- 

 ness to horse serum, 8, 9 



— how rendered hypersensitive 

 to tuberculin, 90 



— hypersensitisation to horse 

 serum in, method of production, 

 17, 18 



— injection of bacterial ana- 

 phylotoxins into, efiEect, 102 



of heated milk into, 



intraperitoneaUy, to produce 

 anaphylaxis, 21 



of horse serum into by 



intracerebral route, 13, 14, 15 



by intraperi- 

 toneal route, 13, 14 



— ■ — of sera into by intra- 

 cranial route, in estimation of 

 toxicity, 34 



-of horse serum into, caus- 

 ing sudden death, 9, 10, 11 



with serum of tuberculous 



sheep, results negative, 89 



— method of producing hyper- 

 sensitiveness to tuberculinin, 89 



— normal and anaphylactic, liver 

 of, perfusion experiments with, 

 129 



— organs used for sensitisation 

 in researches on cellular theory 

 of anaphylaxis, 125, 129 



— sensitisation by injection of 

 milk found impossible, 22, 23 



with bacteria, technique 



for. 85 

 with crystallin of own 



species, 81 

 with crystallin of other 



species, 81, 82 



— ■ egg-albumen, 23 



— • serum, weak doses 



necessary for rapid effect, 16, 17 



tissue extracts, 79 



not specific, 79 



Guinea-pigs, sensitised and nor- 

 mal, effect of injection of egg- 

 albumen into compared, 36 



— — effect of injection of egg- 

 albumen into, in repeated small 

 doses, 59 



injection of diluted un- 



heated serum into proving 

 lethal, 45, 46 



no immunity to anaphy- 

 lactic accidents conferred by 

 peptone on, 109 



passively protected against 



serum anaphylaxis by repeated 

 injections of small doses, 57, 58 



protected against serum 



anaphylaxis, by repeated in- 

 jections of small doses, 57 



rendered anti -anaphylactic, 



can be submitted to resensi- 

 tisation, 75, 76 



to egg-albumen, sensitive 



to injection of anaphylotoxin, 



"3 



with cow's serum, cow's 



milk not toxic to, 36 



with raw or with heated 



egg-albumen, effect of subse- 

 quent injection of heated egg- 

 albumen on, 37, 38 



— spinal anaphylaxis in, pro- 

 duction, 66 



protection against 



by injections in small doses, 66, 

 67 



— test injections of serum in, by 

 intravenous and intracerebral 

 routes, results compared, 30 



— tetanus anaphylotoxin lethal 

 to, 103 



— toxicity of cow's milk and 

 goat's milk compared upon 

 injection into, 35 



of egg-albumen to, varies 



according to route of injection, 



— tuberculous, injection with 

 tuberculin, results, 90, 91 



Heart of anaphylactic guinea-pigs, 



changes in small arteries of, 127 



Heating, toxicity of sera reduced 



by, 53 

 Heat-resisting character of sen- 

 sitising property of serum, 18, 



19 



— — — — — — — more 



marked when serum is diluted, 

 19 



