AN EXPERIMENTAL ANALYSIS OF OEDEMA 



25 



A normal healthy frog, when transferred from water at 

 one temperature to water at another or when left a long 

 period of time in water at one temperature, usually either 

 loses, or remains practically stationary in weight. Should 



Fig. 3 Photograph of a frog with red-leg disease, showing a localized sub- 

 cutaneous oedema of right leg and a generalized subcutaneous oedema of the 

 rest of the body. 



it gain weight, the gain is only temporary, and never does the 

 gain continue through an extended period. On the other hand, 

 when frogs with well-defined external symptoms of red-leg 

 disease remain in water at any temperature within the limits 

 of that of their natural environment, they immediately begin 



