AN EXPERIMENTAL ANALYSIS OF OEDEMA 



29 



TABLE 6 — Continued 



from the foot to the leg, we observe that soon the latter 

 becomes swollen. When, in addition to the foot and leg, the 

 abdominal region becomes affected, a similar swelling of this 

 region becomes evident, and thus the entire body presents 

 the appearance of being swollen generally. The variable 

 manner in which localized oedema manifests itself is essen- 

 tially indicative of the variable manner in which local con- 

 ditions may arise, predisposing to its establishment. 



Frogs usually remain active and respond to stimuli when 

 the oedema is purely localized in character, as when one or 

 both legs are affected. As soon, however, as congestion be- 

 comes more general, and especially when the gastro-intestinal 

 tract is involved, the frogs become weak and sluggish, and 

 soon coma follows. At this time, owing to cardiac inefficiency, 

 the oedema becomes general throughout the body. The ex- 



