478 



MANUAL OF HISTOLOGY. 



other kinds of cells here, although others are stated by Heiderihain to 



exist. "We are supported in this by 

 Rollett. 



(4.) Finally, we come upon the true 

 gland tubule (d). Here the picture 

 is entirely changed. The lumen is 

 bounded by a continuous layer of a 

 special kind of cell, which in many 

 places comes in contact with the mem- 

 brana propria. External to this layer, 

 and as if imbedded in it, we find our old 

 friends the peptic cells, sometimes few, 

 sometimes in large number. The inner- 

 most cells have been named by Heiden- 

 liain " chief cells," and by Rollett ade- 

 The peptic elements, on the other hand, are spoken of 



Fig. 462. Transverse section through the 

 peptic gland of a cat. a, peptic cells ; 6, 

 internal cellular elements ; c, transverse 

 section of the caDilJaries. 



lomorphous cells. 



Fig. 463. Peptic glands from the dog, 

 after Heidenhain; the peptic cells 

 darkened with aniline blue. 1. From 

 a fasting animal. 2. A portion 

 swollen up in the first period of 

 iligestion. 3. Transverse and oblique 

 section of the same. 4. Gland fol- 

 licle at the end of the period of 

 digestion. 



by the first observer as " overlaying cells," 

 and by the latter as " delomorphous " 

 cells. 



These two kinds of cellular elements in 

 the true peptic gland tube may be easily 

 seen in the dog and cat. Transverse sec- 

 tions also show them (fig. 462). In other 

 mammals also essentially similar relations 

 are likewise to be seen (Heidenhain^ 

 Rollett). 



Heidenhairi s observations in regard to 

 the differences to be observed in the ap- 

 pearance of the peptic glands in the states of 

 rest and activity are of great interest further. 



In a fasting dog (fig. 463, 1) the gland 

 tubules appear shrunken, and usually regu- 

 lar in their outline, while their " adelo- 

 morphous" cells are transparent. Some 

 hours after receiving food quite a different 

 appearance presents itself (2, 3). The 

 peptic glands appear swollen, and their 

 walls bulged out at points, the adelomor- 

 phous cells are enlarged and clouded with 

 a finely granular contents. Later on all 

 this swelling up has disappeared (4). The 

 adelomorphous cells are much diminished 

 in volume, but still very rich -in granular 

 matter. 



Which kind of cell now produces the 

 gastric juice, the peptic or adelomorphous? 

 or does one species of cell yield the pepsin 

 and the other the acid 1 



These questions cannot at present be 

 answered. We are inclined to ascribe the 

 greatest importance to the peptic cells, 

 and with Rollett to regard them as con- 

 tractile elements. 



