ON THE PATHOLOGICAL MORPHOLOGY OF SOME ANIMAL FLUIDS. 231 



the largest T 5 ^ ffiha of the size of the blood discs. The smallest glo- 

 bules scarcely exceed in size T-ths of the blood- globules. Plate 8, 

 figs. 29, 30. 



On the fourth, fifth, and sometimes on the sixth days of the eruption, 

 the limpid fluid which is found in the vesicles in small quantity, presents 

 globules almost pellucid, with large and small molecules, and here and 

 there they are provided with central vesicles. Plate 8, figs. 31, 35, 36 ; 

 Plate 9, fig. 45. The molecules which fill the globules exercise a powerful 

 motion even with the envelope broken, (the envelopes are not easily bro- 

 ken.) Animalcules and small globules, as above described, also appear. 



On the fourth, fifth, and sometimes on the sixth and seventh days of 

 the eruption, the fluid contained in the vesicles, has an alkali like 

 the serum of milk. The globules of pus turgid with the larger mole- 

 cules, are increased in number, and exhibit a yellow colour. Globules 

 destitute of molecules are seldom seen in this fluid, and the molecular 

 motion is very evident. In fat individuals, there is sometimes found 

 in it a globule of fat. In some, large, round, or oval globules are 

 seen, exceeding in size the globules of pus four to six times, endowed 

 with the larger molecules, and of a marked yellow colour. The enve- 

 lopes of some of the globules of pus are more quickly broken, and 

 conoid and cylindrical animalcules are also seen. Plate 8, figs. 32, 

 37. 



On the fifth, sixth, and sometimes on the seventh, eighth, and ninth 

 days of the eruption, the fluid in the pustules becomes thicker, and of a 

 deeper yellow colour, and has scarcely any perceptible alkaline re-action. 

 It contains many yellow globules, the envelopes of which are easily 

 broken. Some of the globules are destitute of all envelopes ; but the 

 more the pustules approach the stage of exsiccation, the more intensely 

 the globules are marked of a yellow colour, and the quicker the enve- 

 lopes are broken : hence they become irregular, some corrugated by 

 drying ; others, their envelopes being broken, dissolve, and the mole- 

 cules which they enveloped, I have observed, dispersed without order. 

 The molecular motion at length ceases, and with the fluid may be mixed 

 recent and older cells of epidermis ; this continues until all the fluid 

 which held the globules and molecules suspended in it is evaporated, 

 and inflammation having ceased, is not renewed. Hence a thick pus is 

 continually secreted, until ultimately this becomes dried, turns into a 

 hard crust, which we believe to be made up of a compound of small 

 and large molecules, a few globules of pus, conoid animalcules, and 

 dried cells of epidermis. Plate 8, figs. 33, 34, 3841 ; Plate 9, figs. 

 4750. 



