232 ON THE PATHOLOGICAL MORPHOLOGY OF SOME ANIMAL FLUIDS. 



2. True Human Variola. 



True human variola seldom occurs among us. I have observed this 

 severe pathological process in one individual only. The pellucid 

 lymph from papulae, here and there broken, contains, on the seventh day 

 of the disease, white globules, not perfectly round, but fimbriated on 

 one side as if torn from the place of their growth, [exceeding by four 

 or five times the magnitude of the blood-globules, and which we ob- 

 served to be provided with a pellucid covering and very small molecules. 

 There are, moreover, formed in this fluid, small white or yellowish 

 globules, and also a few globules of the blood. Plate 9, fig. 52. 



Death, which put an end to the disease on the following day, pre- 

 vented, to my sorrow, any ulterior investigation. 



OF LYMPH AND PLASTIC EXUDATION. 



The plastic lymph, an integrant part of the living blood, united to 

 serum and the red particles, constitutes blood. The living blood cir- 

 culating in the organism, when investigated by the microscope, appears 

 composed of two elements : 

 a Of globules ; * and, 



b Of a pellucid fluid, in which the globules float ; the liquor san- 

 guinis : 



Fresh blood taken from the circulatory passages, received in a suffi- 

 ciently deep vessel, and kept at rest for some time at a moderate tempe- 

 rature, coagulates, and its constituent parts separate from each other. 



The globules, on account of their great specific weight, fall to the 

 bottom ; but the liquor sanguinis also divides : 



1st. Into plastic lymph (fibrin) which coagulates, and united with the 

 globules forms the clot, but accumulated on the surface without globules, 

 forms the so-called phlogistic, bufty crust ; and, 



2dly. Into serum, in which the clot floats. 



The globules of the blood are again endowed : 



1st. With an envelope ; and, 



2dly. With a nucleus. 



* Particles or discs would be the more correct appellation for these corpuscles, 

 since all recent microscopical observers agree in opinion that they are not globules ; 

 but, as the author in the original work has given to them the name globuli, the 

 Translator, from a wish to deviate as little as possible from the literal translation, has 

 allowed it to remain. 



