MA11TIN BARRY ON FIBRE. 237 



a free passage given to the contents of the alimentary tube into the 

 peritoneal sac. 



On the fortieth day of the disease, generally no more ulcers are to be 

 detected ; in their place, small smooth depressions of mucous mem- 

 brane are found, provided with no intestinal villi and no follicles ; the 

 peritonaeal serous membrane investing this small part, is remarked of a 

 livid colour. The intermediate net- work, covering the depressed patch 

 of mucous membrane forms oblong and angular areolae. 



On the sixtieth day the depressions of mucous membrane are fur- 

 nished with elongated cylindrical villi, distant from each other, and 

 also with a few simple and shallow follicles. 



The net-work of intermediate vessels forms angular, round, or oval 

 areolse. 



Those mesenteric glands, which lie next the ulcers, most often swell ; 

 they grow red or livid, are rendered softer or more fluid ; the degree and 

 extension of the pathological changes in the glands being seldom found 

 in indirect relation with the changes in the intestine. 



The fluid extricated from the tumid, red, and livid glands, and exa- 

 mined by the microscope, is greyish- white ; it contains, besides some 

 globules of blood, a good many round, white globules, exceeding in ex- 

 tent from three to six times the blood- discs, with a smooth envelope 

 full of the very small molecules. Globules are here found, furnished 

 with one or more central vesicles. Plate 10, figs. 75, 76. 



The changes of the spleen in abdominal typhus, respecting its increase 

 of volume ; of absolute and specific weight ; change of density, and co- 

 lour ; I shall leave to be treated of in another place; here it will be proper 

 to note, that globules occur in the inflamed (hepatized) substance of the 

 spleen endowed with the smaller molecules, which are seldom provided 

 with a smooth envelope, and elongated white corpuscles, the represen- 

 tation or form of which the reader will find in Plate 10, fig. 62. 

 (To be continued.} 



. OBSERVATIONS ON FIBRE.* 



By Martin Barry, M.D., F.R.S.,L. and E. 



THE author observes, that in the mature blood-corpuscles, there 

 is often seen a flat filament already formed within the corpuscle. 



* Extracted from the Annals of Natural History, in the Lond. and Edinb. Journal 

 of Medical Science. In our next number, we intend offering some remarks with 

 reference to this interesting subject. 



