ON THE PATHOLOGICAL MORPHOLOGY OF SOME ANIMAL FLUIDS. 263 



bules, generated by inflammation, appear mixed ; globules, for example, 

 united to mucus, forms catarrhal purulent mucus, &c. ; united to serum, 

 purulent serum, &c. ; united to a white fluid, pus ; mixed with plas- 

 tic lymph, plastic exudation, or purulent plastic exudation. 



The medium with which the globules formed by inflammation appear 

 mixed, then depends (A), upon the organization of the substratum of the 

 pathological process. As long as the texture of the substratum shall not 

 have been destroyed, even so long will there be a special character given 

 to the product of inflammation, which depends upon the special character 

 of the substratum, and not upon any peculiarity of the pathological pro- 

 cess. But as soon as the texture of the substratum of the pathological 

 process shall have been entirely destroyed, then the pathological product 

 of the inflammation loses its special character ; thus, for example, in in- 

 flamed mucous membrane, there is remarked a product of inflammation of 

 a peculiar character, and purulent or puriform mucus is generated, as 

 long as this membrane shall keep its peculiar and characteristic organi- 

 zation, which, being lost, the pathological product is equally deprived 

 of its special character, and in place of puriform or purulent mucus, 

 pus is generated. Hence it is manifest, that the essential difference 

 between pus and mucus is to be sought, not in the globules, but rather 

 in the fluid with which the globules appear mixed. There are not 

 wanting chemical re-agents, by which a clear and distinct difference is 

 evinced by which the product of inflammation of a mucous membrane, 

 whose texture is not altogether destroyed, is distinguished from the 

 product of that membrane whose continuity is injured or organization 

 destroyed ; for, in the destroyed part, the globules of inflammation no 

 longer appear mixed with a medium distinguished by a special character. 



The product of an inflammation, for example, from a suppurating 

 wound of the mucous membrane of the lips of the mouth, is then in no 

 ways distinguishable from the product of inflammation of a suppurating 

 wound of the skin ; but the product of an inflammation of the mucous 

 membrane of the lips, its continuity being uninjured, is distinguished 

 from it in the former case ; for the globules of inflammation in the for- 

 mer case, joined to some limpid fluid, eompose pus ; but the globules 

 in the latter case, mixed with the so-called proper mucus, do not form 

 pus, but puriform or purulent mucus, to be distinguished by re-agents, 

 as long as the organization of this inflamed patch shall not altogether 

 have been destroyed. 



Since the so-called globules of pus generated in every inflammation 

 of mucous membranes are not to be distinguished from each other, 

 whether the continuity be injured or not, which, although even formed 

 from a mucous membrane whose continuity is injured, mixed with some 



