ALCOHOL, DISEASE, AND HEREDITARY DEFECTS 273 



the very decided preponderance of sterile matings and stillborn 

 or short-lived young in the experiments with the alcoholized 

 animals. And the results are all the more convincing because 

 the alcoholized animals had been previously bred and proven 

 capable of bearing normal offspring. 



The following table gives a summary of results up to 191 6: 



Effects of Alcohol on the Descendants of Treated Animals 



Condition of the animals 



Ale. cf X norm. 9 



Norm, cf X ale. 9 



Ale. cf X ale. 9 



Summary 



Control norm, cf x norm. 9 

 9 treated during pregnacy 



and gener. x norm 



2nd gener. x ale 



2nd gener. X 2nd gener.. . . 



3rd gener. x 3rd gener 



3rd gener. x 2nd gener. . . . 



3rd gener. x norm 



3rd gener. x ale 



and, 3rd gener. x 2nd, 3rd 

 gener 



No. of 

 matings 



90 

 33 

 41 



164 



90 



4 



46 



53 



48 



a 



17 



3 



iS 



Neg. Result 

 or early 

 abortion 



37 



7 



20 



64 



22 



o 



10 



16 



29 



20 



IS 



3 



I 



Stillborn 

 litters 



10 

 4 

 4 



2 

 o 



3 

 8 

 7 

 7 

 4 

 4 

 o 



No. of 



Stillborn 



young 



20 

 12 



40 



o 



8 



17 



i5 



14 

 8 

 8 

 o 



Living 

 Litters 



43 

 22 



17 



82 



66 



4 



33 



29 



59 

 21 

 14 

 10 



2 



Young dying 



soon after 



birth 



35 

 23 



12 



70 



19 



I 



29 



22 



43 



19 



16 



S 



2 



Total 

 dead 



55 

 35 

 20 



27 

 I 

 37 

 39 

 59 

 3i 

 24 

 13 



2 



Surviving 

 young 



47 



21 



14 



82 



99 

 7 



25 

 28 

 52 



13 



7 

 7 



I 



More recently additional data were obtained in part from 

 animals of unrelated stock, but the results only confirmed the 

 previous findings. Some of the general comparisons are shown 

 in the following table : 



Progeny of Normal and Alcoholic Guinea Pigs 



Total number 



Lived over 3 months 



Aborted, premature, stillborn . 



Died within 3 months 



Total died 



Defective 



Undersized 



Normal Inhert. 



41 



32 



6 



3 

 9 

 o 



I 



Ale. Inhert. 



302 

 184 

 77 

 41 

 118 

 10 

 II 



