VACCINE-THERAPY 



85 



The following is a table of the average culture age of 

 some of the more common bacteria : 



Icitreus \ 

 albus L 

 aureus \ 



Streptococci 



Pneuinococci 

 B. coli communis ... 

 Micrococcus catarrhalis 

 Micrococcus letragemos 

 Bacillus pyocyaneus 



12 to 48 hours. 



48 to 72 hours. 

 36 to 48 hours. 



4 to 8 hours. 



5 to 10 hours. 

 5 to 10 hours. 

 24 to 36 hours. 



Dose of Autogenous Vaccine to Horses and Cattle. 



The horse and the ox are very tolerant to big doses of 

 vaccines, and in our experience make excellent subjects 

 for sero-vaccine therapy. 



As already stated, when the disease is running a very 

 acute course, smaller doses as a rule should be given ; while, 

 on the contrary, in an animal subject to a chronic bacterial 

 invasion the system is more tolerant to much larger doses. 



When, however, an animal is suffering from an acute 

 staphylococcal infection, a larger proportionate dose of 

 vaccine can be given here than can be given in the case 

 of a streptococcal invasion with a streptococcal vaccine. 

 After three years' experience of immunization with auto- 

 genous vaccines, we find the following range of doses to 

 give the best results, but we would point out the immunizer 

 must ascertain for himself to what extent he may go in 

 dosage with each individual case, remembering that not only 

 does he require to consider the idiosyncrasies of the patient 

 itself, but also the vaccine he is using. In short, there is no 

 absolute rule of thumb to go upon. 



Staphylococci (three kinds) 



Streptococci 



Pneumococci ... 

 Bacillus coli group ... 

 Micrococcus catarrhalis 

 Micrococcus tetragenus 

 Bacillus pyocyaneus 



Minimum. 



250,000,000 

 100,000,000 

 75,000,000 

 200,000,000 

 250,000,000 

 250,000,000 

 250,000,000 



Initial Dose. 

 Optimum. 



500,000,000 

 350,000.000 

 250,000,000 

 350,000,000 

 350,000,000 

 350,000,000 

 350,000,000 



Maximum. 

 750,000,000 

 500,000,000 

 500,000,000 

 750,000,000 

 500,000,000 

 500,000,000 

 500,000,000 



