104 CLINICAL BACTERIOLOGY 



Ulcers. 



Ulcer formations may be seen in any part of the integu- 

 ment. 



They may be single or multiple, benign, and heal with 

 little effort on the part of Nature or the practitioner. They 

 may be malignant, such as cancerous, glanderous, tuber- 

 culous, and incurable. 



Needless to add, vaccine -therapy in the lower animals 

 excludes these three latter conditions. 



When one finds, however, a simple ulcer becoming con- 

 taminated by pathogenic bacteria, and assuming serious pro- 

 portions, with probable symptoms of septic infection or 

 intoxication, the immunizer can do much to relieve suffer- 

 ing and save life with suitable vaccines. 



Invariably the infection is a mixed one, and this point 

 must be definitely settled before curative progress can be 

 embarked upon. 



Locally the curette should be used, and even a single 

 caustic dressing may stimulate healthy granulation, although 

 it must not be repeated. 



When the deep structures of the corium become involved, 

 and if the infection is a virulent one, localized death of 

 tissue may take place. This, of course, must be removed 

 by hot fomentations, the lancet, and free drainage. 



One sometimes meets in practice a destructive and 

 troublesome ulcerative keratitis in valuable dogs after 

 distemper, and one would think a suitable autogenous 

 vaccine would be of great service here, saving eyes and 

 eyesight, which are often lost. Of this, however, the writer 

 has no experience, and only throws out the suggestion should 

 others come across a suitable case to try vaccine-therapy 

 upon. 



