VACCINE-THERAPY 171 



cough, wasting in flesh, and general symptoms of pul- 

 monary lesions, grave suspicions of pulmonary tuberculosis 

 should be aroused. Where the pharyngeal and laryngeal 

 glands become involved, difficulty in swallowing, stertorous 

 respiration, protrusion of the nose, and fulness in these 

 regions is noticed. These may burst at intervals and lead 

 to intermittent discharges from the nose and the tem- 

 porary remission of the symptoms. 



Percussion may reveal little except patchy areas of dul- 

 ness. If pleurisy is present, palpation between the ribs 

 makes the animal grunt or groan. 



When the pleura is acutely involved, as it invariably 

 is when extensive pulmonary disease exists — the visceral 

 pleura through continuity, and the parietal through con- 

 tiguity — friction sounds may be detected, particularly in 

 the early stages, although not always. 



As time goes on the sounds disappear, and where large 

 growths exist, dulness over these areas is present. The 

 coat in these latter stages is dry and staring, the skin being 

 covered with yellow, scaly dandruff; the patient does not lick 

 herself ; the appetite remains in abeyance ; rumination and 

 lactation are both suppressed; and persistent fermentative 

 diarrhoea is greatly in evidence. The eye sinks, and a 

 yellow tinged discharge is often seen from the inner canthus. 

 The muzzle is dry and cold, and the discharges on it are not 

 licked off as in a healthy animal. The respiration becomes 

 shallow, the cough weakens, the extremities are cold, and 

 the animal, in a state of persistent and progressive 

 emaciation, collapses, is unable to rise, death taking place 

 from exhaustion, consequent upon a general toxasmia and 

 inanition. 



Tuberculosis of the Alimentary System. 



Extensive peritoneal lesions may exist, and yet the animal 

 shows no sign of derangement, the condition being often 

 secondary to infection from some other centre. Pressure 

 in an inward and forward direction with the right hand 



