1 68 NORMAL AND PATHOLOGICAL BLOOD. 



polymorphonuclears, while the percentage of the lymphocytes is 

 decreased (2 to 5%) and normal eosinophiles, eosinophilic myelocytes, 

 and large mononuclears make up the remaining percentages. We 

 usually have great numbers of normoblasts. Megaloblasts may be 

 rarely found. The red count is usually about 2,500,000 and the color- 

 index low. 



Lymphatic Leukaemia. In this we have glandular enlargements, 

 but not such large masses as in Hodgkin's disease. The red cells are 

 usually reduced about one-half and the color-index is a little below 

 normal. Normoblasts are rarely found. Myelocytes, as a rule, are 



FIG. 55. Lymphatic leukaemia, p, polymorphonuclear; m, megaloblast; 

 e, eosinopm'le. Twenty-one lymphocytes in this field. (Cabot.} 



absent, but may amount to 5% of the leukocytes. The predominating 

 leukocyte (75 to 98%) is the small lymphocyte. In acute lymphatic 

 leukaemia the large lymphocytes predominate. The leukocyte count is 

 never so great as in myeloid leukaemia, rarely exceeding 125,000. 



Hodgkin's disease is usually considered as a disease with marked 

 glandular enlargements, but with a negative blood picture. Undoubt- 

 edly the view that so-called lymphosarcomata, lymphatic leukaemia and 

 Hodgkin's disease merge into one another and that they represent a 

 malignant cell formation in the haemopoietic system is the conservative 

 one to take. 



