MALARIA. 



189 



iashing movement and break off from the now useless cell carrier and 

 are thereafter termed microgametes. These fertilize the macrogametes 

 and this body now becomes a zygote. 



By a boring-like movement the zygote goes through the walls of the 

 mosquito's stomach, stopping just under the outer epithelial layer of 

 the stomach or mid-gut. It continues to enlarge until about the end of 



.7-0% . 



FIG. 59. Sexual and non- sexual cycle of malaria, i, Schizonts; 2, merocyte; 

 3, merozoites; 4, macrogamete; 5, microgametocyte; 6 and 7, gametes in stomach 

 of mosquito; 8, microgametocyte throwing off microgametes; 9, microgamete fer- 

 tilizing macrogamete; 10, vermiculus or zygote; n and 12, Zygotes; 13, Zygote 

 distended with sporozoites; 14, sporozoites. 



one week it has grown to be about 60 /i in diameter and has become 

 packed with hundreds of delicate falciform bodies. 



Zygotes of benign tertian show little rod-like particles of yellowish 

 pigment those of malignant tertian black clumps, which, however, are 

 not so coarse as those of quartan. 



The mature zygote now ruptures and the sporozoites are thrown off 

 into the body cavity. They make their way to the salivary glands and 



