MEDICINAL USES 



Pharmacopoeia, there was a tincture ml 

 and lupuline was officinal in the Dublii 



" During a recent series of pharmaceutical experiments with 

 the powder, I was constantly struck with the remarkable 

 valerian-like odour evolved from the different preparations, 

 and I was much interested to find, in the course of subse- 

 quent reading on the subject, that M. Personne had discovered 

 valerianic acid in lupuline.* 



"In none of the British Pharmacopoeia preparations of 

 hops, except the extract, can it be said that the real strength 

 of the drug is removed. The tincture made with proof spirit, 

 which does not thoroughly exhaust the active parts of the 

 scales of lupuline, and the watery infusion can but inade- 

 quately represent the virtues of this medicine. 



" The extract of hops, as prepared partly with spirit like 

 the extract of jalap, has the advantage of containing some 

 resin and volatile oil. It is the presence in so considerable 

 an amount of resin, gum, and wax, in lupuline, that renders 

 it important to select a proper solvent, and therefore proof 

 spirit and water respectively are incapable of acting thoroughly 

 upon it. We may, indeed, practically regard lupuline as a 

 gum- resin, and to treat it pharmaceutically with success, we 

 must apply the same solvents as we do in the case of drugs 

 of that class. I have devised a preparation, which I think 

 will prove most useful whenever it is desired to use the hop. 

 It is an ammoniated tincture, and should be made in the 

 same way as the other ammoniated tinctures of the Pharma- 

 copoeia. 



" Like valerian, which also contains an oil and a resin, 



* * Comptes Rendus,' 1854. 



